Related Experiment Video
Updated: Jun 10, 2025

08:46
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
6.3K
Differentiating Multisystem Inflammatory Syndrome From Neonatal Sepsis: A Case Report
Aditi Rawat1, Sagar Karotkar2, Mahaveer S Lakra2
1Neonatology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus
|October 21, 2024
Summary
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause severe multisystem inflammatory syndrome (MIS) in neonates. Transplacental transfer of maternal antibodies and cytokines may contribute to this severe infant immune response.
Area of Science:
- Neonatal immunology
- Pediatric infectious diseases
- Viral pathogenesis
Background:
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a wide range of clinical outcomes.
- Young infants are at higher risk for severe disease.
- The exact cause of multisystem inflammatory syndrome (MIS) in SARS-CoV-2-infected neonates is not fully understood, but immune dysregulation post-infection is suspected.

