Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 9, 2025

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

306

A human cadaveric model for venous air embolism detection tool development.

Nathaniel L Robinson1, Chris Marcellino2,3, Matthew Johnston2

  • 1Department of Cardiovascular Surgery, Mayo Clinic, Rochester, MN, United States of America.

Plos One
|October 21, 2024
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Motivation and perceived learning in serious games: Reflexive thematic analysis of educational escape room experiences.

Medical teacher·2026
Same author

Advancing Perioperative Medication Safety: Consensus Recommendations From the 2024 Anesthesia Patient Safety Foundation Stoelting Conference.

Anesthesia and analgesia·2026
Same author

Statistical learning in childhood: Dimensions, developmental trajectory, and relation with cognitive control.

Child development·2026
Same author

The boundary reproduction number for determining boundary steady state stability in chemical reaction systems.

Journal of mathematical biology·2026
Same author

Counterfactual relief.

Memory & cognition·2025
Same author

Symptomatic Postoperative Pneumocephalus: A Case Series and Review of Management Strategies.

Journal of neurological surgery reports·2025

A human cadaver model was developed to detect venous air emboli (VAE) using mechanical ventilation and modified bypass. This approach aids in developing monitoring technologies while reducing animal and human testing.

Area of Science:

  • Cardiopulmonary bypass
  • Medical simulation

Background:

  • Venous air emboli (VAE) detection is critical during surgery.
  • Current detection methods require further development for automated systems.

Purpose of the Study:

  • To develop a human cadaveric model for investigating automated detection of VAE.
  • To combine mechanical ventilation with modified cardiopulmonary bypass for VAE simulation.

Main Methods:

  • A reversed-flow cardiopulmonary bypass circuit was established in a cadaver.
  • Normal saline was circulated through the heart and lungs.
  • Cannulation involved the aorta (venous) and inferior vena cava (arterial).

Main Results:

  • Preliminary detection of VAE was achieved independently by ventilation and bypass.

More Related Videos

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
06:02

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Published on: April 18, 2013

11.7K
Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
07:57

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

274

Related Experiment Videos

Last Updated: Jun 9, 2025

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

306
Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens
06:02

Anatomical Reconstructions of the Human Cardiac Venous System using Contrast-computed Tomography of Perfusion-fixed Specimens

Published on: April 18, 2013

11.7K
Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
07:57

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

Published on: October 25, 2024

274
  • Pulmonary edema in the cadaver limited simultaneous detection.
  • Feasible air signal detection was confirmed with both limited and radical dissections.

    • Conclusions:

    • A cadaveric model provides a viable platform for developing VAE monitoring technologies.
    • This model reduces the need for animal and human testing in early-stage research.