Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

397
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
397
Glaucoma: Overview01:25

Glaucoma: Overview

516
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
516
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

441
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
441

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward autonomous robotic-assisted and microrobotic surgery.

Science advances·2026
Same author

Comparative Evaluation of Functional Aqueous Humor Outflow in Primary Open Angle Glaucoma versus Primary Angle Closure Glaucoma using Aqueous Angiography.

Journal of glaucoma·2026
Same author

Repeat Exposures to Spaceflight or Bed Rest and Spaceflight-Associated Neuro-Ocular Syndrome Findings.

JAMA ophthalmology·2026
Same author

Aqueous Humour Outflow Assessment Using Imaging-Based Techniques in Angle-Based Minimally Invasive Glaucoma Surgery (MIGS): A Systematic Review.

Clinical & experimental ophthalmology·2026
Same author

Structural Characteristics of Parapapillary Choroidal Microvasculature Dropout in Primary Open-Angle Glaucoma: Comparison Between Width and Area.

Clinical ophthalmology (Auckland, N.Z.)·2026
Same author

Machine-Learning-Based Automated Schlemm's Canal Volumetric Segmentation for Optical Coherence Tomography.

Chemical & biomedical imaging·2026
Same journal

Tracking Synthetic Adhesins on Bacterial Surfaces with Immunofluorescence Microscopy.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Post-Selection Methods for Analyzing mRNA Display Selections and Optimization of Hits.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

High-Performance Computing in Tandem Mass Spectrometry (MS/MS) Peptide Identification.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Engineering and Adapting Disulfide-Containing Proteins to Enable Intracellular Functionality.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

AI-Driven Protein Research: From Prediction to Design.

Methods in molecular biology (Clifton, N.J.)·2026
Same journal

Methods for the In Vitro Selection of Protein and Peptide Libraries Using mRNA Display.

Methods in molecular biology (Clifton, N.J.)·2026
See all related articles

Related Experiment Video

Updated: Jun 9, 2025

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography
10:24

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

13.6K

Aqueous Humor Angiography.

Clemens A Strohmaier1,2, Fiona McDonnell3, Alex S Huang4

  • 1Department of Ophthalmology/Optometry, Kepler University Hospital, Johannes Kepler University, Linz, Austria.

Methods in Molecular Biology (Clifton, N.J.)
|October 21, 2024
PubMed
Summary
This summary is machine-generated.

Aqueous angiography visualizes aqueous humor outflow pathways in the eye. This technique offers high resolution for studying physiological conditions and post-surgery outcomes in both living subjects and tissue samples.

Keywords:
AngiographyAqueous humor outflowGlaucomaIntraocular pressure

More Related Videos

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
05:14

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization

Published on: August 11, 2023

1.0K
Two-Dimensional X-Ray Angiography to Examine Fine Vascular Structure Using a Silicone Rubber Injection Compound
05:26

Two-Dimensional X-Ray Angiography to Examine Fine Vascular Structure Using a Silicone Rubber Injection Compound

Published on: January 7, 2019

5.8K

Related Experiment Videos

Last Updated: Jun 9, 2025

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography
10:24

Detecting Abnormalities in Choroidal Vasculature in a Mouse Model of Age-related Macular Degeneration by Time-course Indocyanine Green Angiography

Published on: February 19, 2014

13.6K
Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
05:14

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization

Published on: August 11, 2023

1.0K
Two-Dimensional X-Ray Angiography to Examine Fine Vascular Structure Using a Silicone Rubber Injection Compound
05:26

Two-Dimensional X-Ray Angiography to Examine Fine Vascular Structure Using a Silicone Rubber Injection Compound

Published on: January 7, 2019

5.8K

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Anatomy

Background:

  • Aqueous humor dynamics are crucial for intraocular pressure regulation.
  • Understanding aqueous humor outflow pathways is key to managing glaucoma.
  • Current imaging techniques have limitations in visualizing these pathways.

Purpose of the Study:

  • To provide a comprehensive guide to aqueous humor angiography.
  • To detail its application in various experimental settings.
  • To highlight its utility in physiological and surgical contexts.

Main Methods:

  • Describes aqueous humor angiography, an anterior segment imaging technique.
  • Covers in vivo and ex vivo experimental setups, including whole-globe and perfusion models.
  • Details material requirements, dye selection, and procedural considerations.

Main Results:

  • Demonstrates the capability of aqueous angiography to visualize conventional/trabecular outflow pathways.
  • Achieves excellent spatial and temporal resolution for detailed imaging.
  • Provides insights into aqueous humor outflow distribution in physiological states and after surgery.

Conclusions:

  • Aqueous angiography is a versatile translational technique for studying aqueous humor outflow.
  • It offers high-resolution imaging for both research and surgical applications.
  • This chapter serves as a practical resource for performing and interpreting the procedure.