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Electron Microscope Tomography and Single-particle Reconstruction

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
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Updated: Jun 9, 2025

Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography

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Published on: January 30, 2016

A data portal for providing standardized annotations for cryo-electron tomography

Utz Ermel¹, Anchi Cheng¹, Jun Xi Ni²

¹Chan Zuckerberg Institute for Advanced Biological Imaging (CZ Imaging Institute), Redwood City, CA, USA.

|October 21, 2024

Summary

No abstract available in PubMed .

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