[Chronic fatigue syndrome in children]

Area of Science:

• Neurology
• Pediatrics
• Immunology

Background:

• Chronic Fatigue Syndrome (CFS) is a complex, debilitating disorder affecting both children and adults.
• Understanding the epidemiology, etiology, and pathogenesis of CFS is crucial for effective management.
• Existing research presents varied perspectives on CFS, necessitating a comprehensive overview.

Purpose of the Study:

• To review scientific literature on Chronic Fatigue Syndrome (CFS).
• To summarize current knowledge on CFS epidemiology, etiology, pathogenesis, and diagnosis.
• To detail clinical manifestations, neurocognitive deficits, and treatment strategies for pediatric CFS.

Main Methods:

• Systematic review of scientific publications on CFS.
• Analysis of studies focusing on epidemiology in children and adults.
• Evaluation of research on CFS etiology, pathogenesis, diagnostic criteria, and clinical features.
• Inclusion of studies on neurocognitive deficits and treatment approaches in pediatric CFS.

Main Results:

• Epidemiological data for CFS in both pediatric and adult populations were reviewed.
• Diverse etiological factors and pathogenetic mechanisms of CFS were presented.
• Current diagnostic criteria and specific clinical manifestations in children were outlined.
• Key neurocognitive deficits in pediatric CFS and therapeutic interventions were discussed.

Conclusions:

• A comprehensive understanding of CFS requires integrating epidemiological, etiological, and clinical findings.
• Accurate diagnosis and tailored treatment are essential for managing CFS, particularly in children.
• Further research into neurocognitive deficits and effective therapies for pediatric CFS is warranted.