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Related Concept Videos

Radiological Investigation II: MRI and Ventilation Perfusion Scan01:30

Radiological Investigation II: MRI and Ventilation Perfusion Scan

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Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
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Magnetic Resonance Imaging01:24

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Related Experiment Video

Updated: Jun 9, 2025

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis
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Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis

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Lung MRI: The future is now.

Jason C Woods1

  • 1Pediatrics and Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Pediatric Pulmonology
|October 22, 2024
PubMed
Summary
This summary is machine-generated.

Magnetic Resonance Imaging (MRI) offers high-resolution structural and functional lung imaging, especially for children unable to perform pulmonary function tests (PFTs). Hyperpolarized Xenon (Xe) MRI precisely detects airway obstruction and gas exchange issues in lung diseases.

Keywords:
BPDMRIhyperpolarizedlungprematurityxenon

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Related Experiment Videos

Last Updated: Jun 9, 2025

Author Spotlight: Enhancing Diagnostic Strategies and Biomarker Development for Comprehensive Lung Function Analysis
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Author Spotlight: Optimized Lung MRI Protocol with Computationally Efficient Reconstruction Methods
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282
Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging
10:44

Three-Dimensional Phase Resolved Functional Lung Magnetic Resonance Imaging

Published on: June 21, 2024

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Area of Science:

  • Medical Imaging
  • Pulmonology
  • Pediatric Medicine

Background:

  • Magnetic Resonance Imaging (MRI) provides high-resolution structural imaging and can reveal functional abnormalities during respiration.
  • In pediatric patients with chronic lung diseases, MRI is a safe alternative to pulmonary function tests (PFTs) for characterizing cardiorespiratory conditions.
  • Hyperpolarized Xenon (Xe) MRI is highly sensitive to regional airway obstruction, alveolar-airspace changes, and gas-exchange abnormalities.

Purpose of the Study:

  • To summarize the functional measures currently available using hyperpolarized Xenon MRI for lung imaging.
  • To highlight the utility of MRI in pediatric populations with chronic lung diseases.

Main Methods:

  • Utilizing tomographic imaging via MRI to capture structural and functional lung abnormalities.
  • Employing functional lung imaging with hyperpolarized Xe MRI to assess regional airway obstruction, alveolar-airspace size/structure, and gas-exchange.
  • Routine application of Xe MRI in patients aged 5 and above.

Main Results:

  • MRI effectively characterizes cardiorespiratory disease in infants and children where PFTs are not feasible.
  • Hyperpolarized Xe MRI demonstrates high sensitivity to various lung pathologies, including interstitial abnormalities and blood-flow issues.
  • The technique provides detailed insights into regional lung function.

Conclusions:

  • MRI is a safe and effective imaging tool for pediatric lung diseases.
  • Hyperpolarized Xe MRI offers comprehensive functional assessment of the lungs.
  • This summary provides an overview of available Xe MRI functional measures for clinical use.