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Updated: Jun 9, 2025

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Cervical Cancer Screening: Patient Perspectives on Transitioning to Primary High-Risk Human Papillomavirus Testing
Larissa L White1, Shauna R Goldberg1, Alison G Escobar2
1Institute for Health Research, Kaiser Permanente Colorado , Aurora, CO, USA.
Patients expressed concerns about reduced cervical cancer screening frequency potentially leading to underdiagnosis of STIs. Clearer education on primary human papillomavirus (HPV) testing rationale and in-person communication are preferred for the screening transition.
Area of Science:
- Gynecology
- Public Health
- Preventive Medicine
Background:
- Updated 2018 cervical cancer screening guidelines recommend primary human papillomavirus (HPV) testing every 5 years.
- Primary HPV screening uptake has been lower than anticipated, necessitating investigation into patient perspectives.
Purpose of the Study:
- To evaluate patient perspectives on transitioning from cotesting to primary HPV testing for cervical cancer screening.
- To identify patient concerns and preferences regarding updated screening protocols.
Main Methods:
- Conducted semistructured phone interviews with 16 individuals aged 30-65.
- Explored reactions to screening changes, cancer risk concerns, educational material feedback, and communication preferences.
Main Results:
- Patients worried that less frequent screening could lead to underdiagnosis of sexually transmitted infections (STIs).
- Participants desired clear explanations of the rationale for primary HPV testing in educational materials.
- In-clinic communication between patient and practitioner was the preferred method for discussing screening changes.
Conclusions:
- Patient concerns include differentiating cervical cancer and STI screening and potential underdiagnosis.
- Findings can guide health systems in addressing patient concerns during the shift to primary HPV testing for cervical cancer screening.
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07:43Four-color Fluorescence Immunohistochemistry of T-cell Subpopulations in Archival Formalin-fixed, Paraffin-embedded Human Oropharyngeal Squamous Cell Carcinoma Samples
Published on: July 29, 2017
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