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Manufacturing, Processing, and Characterization of Self-Expanding Metallic Stents: A Comprehensive Review.

Saeedeh Vanaei1, Mahdi Hashemi2, Atefeh Solouk3

  • 1Mechanical Industrial and Manufacturing Engineering Department, University of Toledo, Toledo, OH 43606, USA.

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|October 25, 2024
PubMed
Summary

This review explores advancements in nitinol (NiTi) self-expanding stents, highlighting challenges and opportunities. It covers multidisciplinary aspects and additive manufacturing for improved patient outcomes.

Keywords:
additive manufacturingbiomaterialsbiomimicrypatency rateself-expanding metallic stentsshape memory alloy

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Area of Science:

  • Biomaterials Science
  • Medical Device Engineering
  • Materials Science

Background:

  • Nitinol (NiTi) is a key alloy for self-expanding stents due to its shape memory and superelastic properties.
  • Current stent technology faces challenges in optimizing patient outcomes and device performance.
  • A comprehensive review of multidisciplinary aspects is needed to guide future stent development.

Purpose of the Study:

  • To review the state of the art in nitinol self-expanding stents.
  • To identify challenges and opportunities for improving patient outcomes with NiTi stents.
  • To highlight the role of additive manufacturing in advancing metal stent technology.

Main Methods:

  • Extensive literature review covering design, simulation, materials, manufacturing, and testing.
  • Analysis of multidisciplinary factors influencing stent performance and biocompatibility.
  • Focus on emerging trends, particularly additive manufacturing techniques.

Main Results:

  • Nitinol stents exhibit significant potential for enhanced performance and patient outcomes.
  • Additive manufacturing offers transformative possibilities for novel stent designs and functionalities.
  • Multidisciplinary approaches are crucial for addressing current limitations in stent technology.

Conclusions:

  • This review consolidates knowledge on nitinol stents, providing a roadmap for innovation.
  • Future research should focus on optimizing design, materials, and manufacturing processes.
  • Advancements in additive manufacturing hold promise for next-generation nitinol stents.