Global Cancer Nurse's Experiences and Perceptions of Potential Occupational Exposure to Cytotoxic Drugs: Mixed Method...

Area of Science:

• Oncology Nursing
• Occupational Health and Safety
• Pharmacology

Background:

• Cancer nurses face potential occupational exposure to cytotoxic drugs (CDs) during handling and administration.
• Existing knowledge on nurses' perceptions and experiences of this exposure is fragmented.
• A comprehensive understanding is needed to ensure safe nursing practices.

Purpose of the Study:

• To conceptualize the experiences and perceptions of cancer nurses regarding occupational exposure to cytotoxic drugs.
• To identify factors influencing these perceptions and experiences.
• To inform strategies for improving safety protocols.

Main Methods:

• A mixed-methods systematic review was conducted.
• Framework synthesis was employed to analyze findings from 38 studies.
• Literature search performed across major databases (CINAHL, PubMed, Web of Science, Ovid Nursing, PsycINFO) in February 2022, adhering to PRISMA guidelines.

Main Results:

• Identified new categories: perceived solutions, side effects, and risky behaviors associated with cytotoxic drug handling.
• Revealed three levels of experience and perception: individual, shared, and cultural.
• Highlighted a discrepancy between espoused safe practices and experienced realities.

Conclusions:

• Cancer nurses generally endorse safe handling and administration of cytotoxic drugs.
• A complex interplay exists between self-reported perceptions and observed experiences of occupational exposure.
• There is a notable difference between perceived and actual practice, necessitating objective assessment.