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Postoperative complications in patients with Behçet's disease
You Jin Jung1, Eun Hye Park2,3, Ju Yeon Kim4,5
1Division of Rheumatology, Department of Internal Medicine, Seoul Metropolitan City Seoul Medical Center, Seoul, Republic of Korea.
Clinical Rheumatology
|October 30, 2024
Summary
Patients with Behçet
Area of Science:
- Medical research
- Surgical outcomes
- Inflammatory diseases
Background:
- Behçet's disease (BD) is a rare multisystem inflammatory disorder.
- Surgical risks in BD patients are not well-defined.
- Understanding postoperative complications is crucial for patient management.
Purpose of the Study:
- To determine the frequency of postoperative complications in patients with Behçet's disease.
- To compare surgical complication risks between BD patients and matched controls.
Main Methods:
- Retrospective analysis of 389 BD patients undergoing surgery (2003-2019).
- 1:1 matched controls based on age, sex, and surgery type.
- Generalized estimating equation analysis for complication comparison.
Main Results:
- 5.7% of surgeries in BD patients had complications (dehiscence, bleeding, infection).
- Complications were higher after cardiovascular (33.3%) and vascular (22.2%) surgeries.
- BD patients had higher risks of complications (OR 3.4) and reoperation (OR 5.2) after cardiovascular surgery compared to controls.
Conclusions:
- Postoperative complication risk in Behçet's disease varies by surgery type.
- Cardiovascular surgery poses increased risks for BD patients.
- Ophthalmic surgery appears safe in BD patients, comparable to controls.
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