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Related Concept Videos

Hypertension and Regulation of Blood Pressure01:18

Hypertension and Regulation of Blood Pressure

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Hypertension, the most common cardiovascular disease, is diagnosed through repeated measurements of elevated blood pressure. Its risks, including damage to the kidney, heart, and brain, are directly proportional to blood pressure levels. Starting from 115/75 mm Hg, the risk of cardiovascular disease doubles with each increment of 20/10 mm Hg. The diagnosis relies on blood pressure measurements, not on patient symptoms, as hypertension is often asymptomatic until end-organ damage is imminent or...
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Coronary Artery Disease IV: Medical Management01:26

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Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
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Assessment of blood pressure in brachial artery(one-step method)01:15

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This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
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Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers01:26

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Receptor tyrosine kinase inhibitors (TKIs) and calcium channel blockers (CCBs) are two critical categories of drugs employed in the treatment of pulmonary artery hypertension (PAH). PAH is a disease that causes high blood pressure in the pulmonary arteries, resulting in chest pain, fatigue, and shortness of breath.
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Antihypertensive Drugs: Angiotensin II Receptor Blockers01:30

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In the renin-angiotensin-aldosterone system, a hormone called angiotensin II plays a crucial role. It binds to the AT1 receptors in vascular smooth muscles coupled with Gq proteins. The activation of these receptors activates an enzyme called phospholipase C, which releases two molecules: inositol trisphosphate and diacylglycerol. These molecules cause a chain reaction that leads to the phosphorylation of myosin light chains and promotes interaction between actin and myosin, leading to smooth...
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Pre-Procedural Guidelines for Assessing Blood Pressure01:10

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Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
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Related Experiment Video

Updated: Jun 9, 2025

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
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[Arterial hypertension-Current recommendations for action].

Milen Babic1, Oliver Vonend2, Markus van der Giet3

  • 1Klinik für Nephrologie und internistische Intensivmedizin, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Deutschland. milen.babic@charite.de.

Innere Medizin (Heidelberg, Germany)
|October 30, 2024
PubMed
Summary

Arterial hypertension (aHT) affects many, with suboptimal treatment risking severe events. This article summarizes new German and European guidelines for better hypertension management and prevention of organ damage.

Keywords:
GuidelinesHypertension-mediated organ damageLifestyle risk reductionPatient adherenceTreatment resistance

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Area of Science:

  • Cardiology
  • Nephrology
  • Public Health

Context:

  • Arterial hypertension (aHT) prevalence is high and increasing in Germany, affecting nearly one in three individuals.
  • Only 50% of treated patients achieve controlled blood pressure, increasing risks of cardiovascular and renal events.
  • Suboptimal hypertension management can lead to fatal outcomes.

Purpose:

  • To provide a practical summary of the current diagnostics and treatment recommendations from both the German national treatment guidelines (NVL) and the European Society of Hypertension (ESH) 2023.
  • To discuss relevant differences between the two guideline updates.
  • To offer routinely applicable advice for healthcare professionals.

Summary:

  • Both new guidelines emphasize avoiding hypertension-mediated organ damage (HMOD) and identifying high blood pressure.
  • Preventive measures, lifestyle recommendations, and simplified target blood pressure values are highlighted for routine practice.
  • The article offers a comparative overview of diagnostic and therapeutic strategies.

Impact:

  • Aims to improve the routine management of arterial hypertension by integrating new guideline recommendations.
  • Facilitates better identification and prevention of hypertension-related complications, including organ damage.
  • Supports healthcare providers in making informed decisions for patient care and treatment optimization.