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Updated: Jun 9, 2025

Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
Advances in triterpene drug discovery
Zoë R Goddard1, Mark Searcey2, Anne Osbourn1
1Department of Biochemistry and Metabolism, John Innes Centre, Norwich Research Park, Colney Lane, Norwich NR4 7UH, UK.
Abstract:
Triterpenes are structurally complex natural products with promising therapeutic properties. Recalcitrance to chemical synthesis has hindered their use in drug development. Recent advances now make it possible to access and harness triterpene structural diversity using engineering biology approaches, enabling the discovery and optimisation of a new generation of drug leads.
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