Classification of coronary artery disease severity based on SPECT MPI polarmap images and deep learning: A study on

Jui-Jen Chen1, Ting-Yi Su2, Chien-Che Huang3

  • 1Department of Nuclear Medicine, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung.

Digital Health
|November 1, 2024
PubMed

Insights

Deep learning accurately predicts multivessel disease (MVD) using SPECT MPI scans, improving coronary artery disease assessment. This approach offers efficient diagnosis and potential cost savings.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Artificial Intelligence

Background:

  • Coronary artery disease (CAD) is a major global health issue.
  • Single photon emission computed tomography myocardial perfusion imaging (SPECT MPI) is used to assess CAD severity.
  • Manual interpretation of SPECT MPI can lead to errors; deep learning offers automated analysis.

Purpose of the Study:

  • To apply deep learning for assessing CAD severity and identifying multivessel disease (MVD).
  • To evaluate the efficacy of the EfficientNet-V2 model combined with DeepSMOTE for MVD prediction using SPECT MPI images.

Main Methods:

  • Utilized the EfficientNet-V2 deep learning model.
  • Employed DeepSMOTE for data augmentation and model training.
  • Analyzed a dataset of 254 patients with SPECT MPI images.

Main Results:

  • Achieved an accuracy of 84.31% in predicting MVD.
  • Obtained an area under the receiver operating characteristic curve (AUC) of 0.8714 for MVD prediction.
  • Successfully distinguished between MVD and single-vessel disease (SVD).

Conclusions:

  • Deep learning techniques are feasible for predicting MVD from SPECT MPI images.
  • The EfficientNet-V2 and DeepSMOTE integration effectively assesses CAD severity and differentiates MVD.
  • This approach enables early MVD prediction, potentially improving patient outcomes and reducing costs.
Abstract