Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Contralateral delay activity as a marker of visual working memory capacity: A multi-site registered replication.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same author

An Aha moment precedes the strategic response to a visuomotor rotation.

Current biology : CB·2026
Same author

No Evidence of Transfer of Learning Between Problem-Solving Tasks Using Different Transformation Rules.

Open mind : discoveries in cognitive science·2026
Same author

Investigating the reproducibility of the social and behavioural sciences.

Nature·2026
Same author

Investigating the replicability of the social and behavioural sciences.

Nature·2026
Same author

Investigating the analytical robustness of the social and behavioural sciences.

Nature·2026

Related Experiment Video

Updated: Jun 8, 2025

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
10:37

Transcranial Direct Current Stimulation tDCS for Memory Enhancement

Published on: September 18, 2021

13.7K

Theta Transcranial Alternating Current Stimulation Is Not Effective in Improving Working Memory Performance.

Dauren Kasanov1, Olga Dorogina1, Faisal Mushtaq2,3

  • 1Ural Federal University.

Journal of Cognitive Neuroscience
|November 1, 2024
PubMed
Summary

Theta frequency transcranial alternating current stimulation (tACS) applied to the midline does not effectively enhance working memory (WM) performance, according to two experiments. Further research is needed to explore alternative methods for cognitive enhancement.

More Related Videos

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation
11:11

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

Published on: September 23, 2017

9.0K
Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation tACS
06:51

Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation tACS

Published on: January 22, 2016

14.3K

Related Experiment Videos

Last Updated: Jun 8, 2025

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
10:37

Transcranial Direct Current Stimulation tDCS for Memory Enhancement

Published on: September 18, 2021

13.7K
Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation
11:11

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

Published on: September 23, 2017

9.0K
Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation tACS
06:51

Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation tACS

Published on: January 22, 2016

14.3K

Area of Science:

  • Neuroscience
  • Cognitive Science
  • Brain Stimulation

Background:

  • Frontal midline theta activity (4-8 Hz) is strongly linked to working memory (WM) performance.
  • Transcranial alternating current stimulation (tACS) can induce lasting changes in brain oscillatory activity.

Purpose of the Study:

  • To investigate if tACS targeting dorsomedial PFC and ACC can improve WM by modulating frontal midline theta.
  • To assess both after-effects and online effects of tACS on WM.

Main Methods:

  • Two experiments involving tACS (6 Hz, 1 mA) applied to Fpz-CPz in healthy participants.
  • EEG recordings during WM tasks involving information retention and manipulation.
  • Comparison of verum (active) stimulation with sham (placebo) stimulation.

Main Results:

  • No significant improvements in behavioral WM performance were observed with theta tACS.
  • No changes in theta activity were detected after stimulation.
  • Alpha activity modulation during WM tasks differed between verum and sham conditions, but did not translate to performance gains.

Conclusions:

  • Theta frequency tACS applied at the midline is not an effective method for enhancing working memory.
  • The findings suggest current tACS protocols targeting frontal midline theta may not be suitable for cognitive enhancement of WM.