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Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

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MACULAR OUTER RETINAL ATROPHY AFTER VITRECTOMY AND HYPOTONY: TWO CASES.

Chloe Y Li¹, Erin E Flynn, Stanley Chang

¹Edward S Harkness Eye Institute, Columbia University Medical Center/New York Presbyterian, New York, New York.

Retinal Cases & Brief Reports

|November 1, 2024

Summary

Hypotony, or low eye pressure, after vitrectomy surgery can rarely lead to focal outer retinal atrophy. This condition involves damage to the retina and choroid, potentially causing vision loss.

Keywords:

hypotony maculopathy macular atrophy surgical complication

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Area of Science:

Ophthalmology
Retinal Surgery
Ocular Pathology

Background:

Vitrectomy is a common surgical procedure for various retinal conditions.
Post-operative hypotony can occur after vitrectomy and has potential complications.
Focal outer retinal atrophy is a degenerative condition affecting the outer layers of the retina.

Purpose of the Study:

To describe two cases of focal outer retinal atrophy and hypotony following vitrectomy.
To investigate the relationship between post-vitrectomy hypotony and retinal atrophy.

Main Methods:

Retrospective review of medical records for two patients treated between 2019 and 2023.
Detailed analysis of surgical history, post-operative course, and ophthalmologic examinations.

Main Results:

Patient 1 developed hypotony and focal outer retinal atrophy after vitrectomy, epiretinal membrane peel, and cataract extraction, resulting in a paracentral scotoma.
Patient 2 experienced hypotony with macular folds after IOL exchange surgery, followed by focal chorioretinal atrophy and reduced central vision.
Both cases demonstrated stable areas of atrophy despite normalization of intraocular pressure.

Conclusions:

Hypotony after vitrectomy is a rare but potential risk factor for developing focal chorioretinal atrophy.
Early recognition and management of post-vitrectomy hypotony may be crucial.
Further research is needed to understand the mechanisms and long-term implications of this complication.