Adaptive Approach to Treating Cervical Cancer in a Patient With Dramatic Uterine Movement

Adaptive radiation therapy is a modern technological advancement that allows radiation treatments to be adjusted daily to account for changes in the patient's anatomy, such as bladder and rectal filling, as well as changes in the tumor volume and position. In this case report, we present a patient with locally advanced cervical cancer who received definitive radiation therapy of 4500 cGy in 25 fractions using the Varian's Ethos system. We observed substantial daily uterine movement, which required re-optimization of each treatment fraction. Without the daily plan adaptation, the treatment would have resulted in markedly suboptimal dose coverage to the tumor. This case report highlights the importance of adaptive radiotherapy in managing anatomical changes in cervical cancer treatment and improving outcomes.