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[Research progress on the development of myopia prediction models and their predictive performance].
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|November 6, 2024
Summary
Accurate myopia prediction and early intervention are crucial for slowing progression and reducing societal burden. This review covers models using ocular metrics, environmental, and genetic factors, plus AI, for personalized myopia control.
Area of Science:
- Ophthalmology
- Public Health
- Biomedical Engineering
Background:
- Myopia incidence is rising globally, particularly in China, necessitating effective prevention and control strategies.
- Early prediction and intervention are vital for mitigating myopia progression and its associated societal costs.
- Existing prediction models vary in approach, highlighting the need for comprehensive reviews.
Purpose of the Study:
- To review recent advancements in myopia prediction models and evaluate their performance.
- To explore diverse predictive factors including ocular characteristics, environmental influences, and genetic markers.
- To examine the role of artificial intelligence in enhancing myopia prediction accuracy.
Main Methods:
- Review of literature on myopia prediction models, encompassing refractive power and ocular biological characteristics (e.g., axial length).
- Analysis of models incorporating environmental factors (e.g., age of onset, parental myopia, education, living conditions).
- Inclusion of genetic factor-based models (parental myopia, SNPs from GWAS) and artificial intelligence applications (machine learning, deep learning).
Main Results:
- Models utilizing refractive power and ocular biometrics offer valuable predictive insights.
- Environmental and genetic factors significantly correlate with myopia development in school-aged children.
- AI algorithms demonstrate potential for predicting axial length growth and refractive power changes with high accuracy.
Conclusions:
- Advances in myopia prediction models provide a foundation for more precise and personalized interventions.
- Integrating diverse data sources (ocular, environmental, genetic, AI) can improve predictive accuracy.
- Enhanced myopia prediction is key to effective, individualized prevention and control strategies.

