Outer-surface adduct formation and selective separation of cis-type gallated and cis-type non-gallated catechins
Hiroyuki Tsutsumi1, An Miura1, Asuka Hanada1
1Faculty of Pharmaceutical Sciences, Fukuoka University, 8-19-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan. h-tsutsumi@fukuoka-u.ac.jp.
Abstract:
We found that cis-type gallated and non-gallated catechins form low water solubility outer-surface adducts with cucurbit[7]uril in aqueous solution, with cis-type gallated catechins showing a higher tendency to precipitate as outer-surface adducts. By exploiting this phenomenon, we achieved the selective separation of cis-type gallated and non-gallated catechins in solution.
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