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Updated: Sep 12, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Sleep apnea in infants and the risk of SIDS]
Insights
Infants at risk for Sudden Infant Death Syndrome (SIDS) exhibit more frequent and prolonged apneas (breathing pauses) during sleep compared to healthy infants. These infants also show a higher incidence of pathological gastroesophageal reflux.
Area of Science:
- Pediatric Sleep Medicine
- Neonatology
- Respiratory Physiology
Abstract:
The examination of the respiratory function in 184 sleeping infants gave evidence of a significant difference in several parameters between the so-called SIDS risk group and the control group. The risk group (97 babies) consists of 60 infants with frequent prolonged apneas, 30 infants with postnarcotic apneas and 7 near miss infants. Polygraphic registration during sleep showed significantly more apneas in the risk group. These apneas often appeared more frequently during certain periods. The average respiratory deficit expressed as the MA-value (MA = average apnea duration) in the risk group was significantly higher than in control infants. Besides that we were able to prove a more frequent pathological gastroesophageal reflux in the risk infants than in control infants.
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