PLASMA MEMBRANE RICH IN GROWTH FACTORS FOR THE TREATMENT OF MACULAR HOLES ASSOCIATED WITH MACULAR TELANGIECTASIA TYPE...

The aim of the study is to demonstrate the regenerative effects of plasma membrane rich in growth factors as an adjuvant in the surgical treatment of full-thickness macular holes associated with macular telangiectasia Type 2.

Observational study of a consecutive case series involving Type 2 macular telangiectasia patients with full-thickness macular holes. Best-corrected visual acuity, optical coherence tomography data, anatomical closure rates, and duration of follow-up were documented.

Three patients who met the inclusion criteria were enrolled: two were naive and one was already operated with silicon oil in situ. Median follow-up was 6 months (range 6-18 months), anatomical closure rate was 100%, and median visual acuity change was 20/60 (range 20/40-20/100). No complications related to plasma membrane rich in growth factors were found.

Plasma membrane rich in growth factors is a valuable option for the treatment of full-thickness macular holes associated with macular telangiectasia Type 2. Its application promotes tissue regeneration and facilitates anatomical closure. The technique is reproducible and does not require manipulation of the internal limiting membrane.