Validation of a Novel Suprathreshold Strategy for Screening Visual Function

Area of Science:

• Ophthalmology
• Medical Devices
• Diagnostic Tools

Background:

• Glaucoma, a major cause of blindness, is linked to high intraocular pressure (IOP) and retinal cell loss.
• Visual field (VF) testing is crucial for diagnosing and monitoring glaucoma.
• Suprathreshold VF tests offer a faster screening alternative to threshold strategies.

Purpose of the Study:

• To evaluate the TEMPO/IMOvifa suprathreshold visual field screening program.
• To assess its sensitivity in a glaucoma cohort and specificity in a healthy cohort.

Main Methods:

• A single-site study involving 193 subjects (101 healthy, 92 glaucoma).
• Subjects underwent comprehensive ocular exams and TEMPO suprathreshold VF tests.
• A threshold VF test accompanied the suprathreshold testing.

Main Results:

• Average suprathreshold test time was 39.4 seconds per eye.
• Specificity was 91% in healthy individuals.
• Overall sensitivity was 49%, but 100% for glaucoma with MD < -3 dB.

Conclusions:

• The TEMPO screening program exhibits strong specificity for healthy cases.
• It shows significant sensitivity for mild to moderate glaucoma.
• Complementary tests like OCT and threshold perimetry are recommended for early glaucoma diagnosis.