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Associations Among Cardiometabolic Risk Factors, Sleep Duration, and Obstructive Sleep Apnea in a Southeastern US
Adam P Knowlden1, Lee J Winchester2, Hayley V MacDonald2
1Department of Health Science, The University of Alabama, Tuscaloosa, AL, United States.
JMIR Formative Research
|November 8, 2024
Summary
Short sleep and obstructive sleep apnea are linked to cardiometabolic disease risk factors. This study found significant associations between sleep duration, apnea, BMI, blood pressure, triglycerides, and glucose levels.
Area of Science:
- Public Health
- Cardiology
- Sleep Medicine
Background:
- Short sleep and obstructive sleep apnea (OSA) are prevalent public health issues.
- Over 35% of US adults report insufficient sleep, and more than 80% of OSA cases remain undiagnosed.
- Understanding the link between sleep and cardiometabolic disease is crucial but challenging.
Purpose of the Study:
- To report initial findings from the Short Sleep Undermines Cardiometabolic Health-Public Health Observational study (SLUMBRx-PONS).
- To investigate the associations between sleep indices and cardiometabolic disease risk factors.
Main Methods:
- Cross-sectional and longitudinal data from 47 participants in a rural US community.
- Sleep assessed via wrist actigraphy (total sleep time, TST7N) and home sleep apnea testing (apnea-hypopnea index, AHI).
- Cardiometabolic risk factors included BMI, blood pressure, triglycerides, and glucose.
Main Results:
- Total sleep time (TST7N) was associated with AHI, BMI, systolic, and diastolic blood pressure.
- Apnea-hypopnea index (AHI) was associated with TST7N, BMI, triglycerides, and glucose.
- Sleep indices and cardiometabolic factors explained significant variance in each other, highlighting a complex interplay.
Conclusions:
- The SLUMBRx-PONS study reveals a complex relationship between sleep and cardiometabolic health.
- Further research with clinical, epidemiological, and ambulatory measures is needed.
- Findings can inform public health interventions for the cardiometabolic consequences of inadequate sleep.
Keywords:
SLUMBRx studyShort Sleep Undermines Cardiometabolic Health-Public Health Observational studyadipositycardiometaboliccardiometabolic diseaseobesityobstructive sleep apnearisk factorssleepsleep apneasleep durationMore Related Videos
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