CT, MRI, and PET Imaging in Patients with Traumatic Brain Injury

Traumatic brain injury (TBI) is a major health concern in the United States and worldwide. Neuroimaging is a critical element in the clinical evaluation of TBIs, as computed tomography (CT) and MR imaging are commonly used to identify structural changes that may aid in treatment decision-making and long-term patient monitoring. This article reviews the utility of CT and MR imaging while focusing on the emerging applications of PET in TBI. Pertinent research findings in the molecular imaging of cerebral metabolism, tau and β-amyloid, neurotransmitters, and neuroinflammation are discussed.