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Lewis Acid Promotes Three-Component Cyclization to Construct Dithioxazole Derivatives

Kai Zou1, Anquan Li1, Yitong Chen1

  • 1School of Chemistry and Chemical Engineering, Guangdong Pharmaceutical University, Zhongshan 528458, P. R. China.

The Journal of Organic Chemistry
|November 16, 2024
PubMed
Summary

A new three-component reaction efficiently synthesizes disulfide-substituted oxazole derivatives. This transition-metal-free method offers a simple and effective route with good functional group tolerance and regioselectivity.

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