Visual simulation of intraocular lenses: from on-bench performance to computational and experimental validations

Area of Science:

• Ophthalmology and Optometry
• Optical Engineering
• Computational Optics

Background:

• Intraocular lenses (IOLs) are crucial for vision correction after cataract surgery.
• Accurate simulation of IOL performance is essential for predicting visual outcomes.
• Existing simulation methods may not fully capture the complex optical characteristics of modern IOLs.

Purpose of the Study:

• To present a systematic method for simulating various intraocular lenses (IOLs).
• To evaluate the accuracy of the proposed simulation method by comparing computed and experimental results.
• To demonstrate the utility of the simulation technique for understanding IOL design performance.

Main Methods:

• Five different IOLs (two trifocal, one bifocal, one enhanced monofocal, one extended depth of focus) were evaluated.
• Through focus visual Strehl (TFVS) was measured using the OptiSpheric IOL PRO2 device.
• Estimated TFVS (ETFVS) and temporal coefficients were computed for simulation via temporal multiplexing (SimVis TFVS).
• Experimental SimVis TFVS was acquired using a high-speed focimeter.

Main Results:

• High correlation was found between computed (ETFVS, SimVis TFVS) and experimental (experimental SimVis TFVS) data.
• Cross-correlation coefficients exceeded 0.94 for ETFVS vs. SimVis TFVS and 0.97 for experimental SimVis TFVS vs. SimVis TFVS.
• Root mean square error (RMSE) was below 0.05 for all evaluated IOLs.

Conclusions:

• The developed systematic method accurately simulates the visual performance of various IOL designs.
• The simulation technique, using temporal multiplexing, provides reliable temporal coefficients for visual simulations.
• This approach enables a deeper understanding of how different IOL designs impact visual quality.