Related Experiment Video
Updated: Jun 7, 2025

08:46
Spinal Cord Lateral Hemisection and Asymmetric Behavioral Assessments in Adult Rats
Published on: March 24, 2020
14.4K
Neurologic Decline After Spinal Cord Injury
Zakari R Dymock1, Sara Shahid Salles1
1Department of Physical Rehabilitation and Rehabilitation, University of Kentucky College of Medicine, 2050 Versailles Road, Lexington, KY 40504, USA.
Physical Medicine and Rehabilitation Clinics of North America
|November 20, 2024
Summary
Spinal cord injuries (SCI) can lead to ongoing neurological issues. This review details managing spasticity, pain, and spine complications in chronic SCI patients.
Area of Science:
- Neurology
- Neurosurgery
- Rehabilitation Medicine
Background:
- Spinal cord injuries (SCI) induce significant anatomical and physiological changes.
- Understanding these changes is crucial for effective healthcare management.
- Focusing on subacute to chronic stages reveals progressive neurological decline.
Purpose of the Study:
- To detail the neurological impairments following spinal cord injury in subacute to chronic phases.
- To provide an overview of current management strategies for these complications.
- To highlight key areas of concern for healthcare providers managing chronic SCI.
Main Methods:
- Literature review focusing on subacute and chronic stages of SCI.
- Analysis of changes in spasticity, neuropathic pain, and secondary spinal complications.
- Inclusion of management strategies for dual-diagnosis TBI and SCI.
- Examination of other neurologic complications like mononeuropathies.
Main Results:
- Neurological decline in chronic SCI involves progressive spasticity, neuropathic pain, and spinal complications.
- Management strategies evolve over time, requiring adaptive approaches.
- Co-occurring traumatic brain injury (TBI) presents unique challenges in SCI management.
- Late-onset complications such as upper-extremity mononeuropathies are common.
Conclusions:
- Effective management of chronic SCI requires addressing evolving neurological deficits.
- Multidisciplinary care is essential for optimizing outcomes in patients with SCI.
- Continued research is needed to improve long-term management and quality of life for SCI survivors.
Related Concept Videos
Neurogenesis and Regeneration of Nervous Tissue
724
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
724
Spinal Cord
413
The spinal cord, a critical component of the central nervous system, extends from the base of the brainstem to the lumbar region of the vertebral column. It is essential for maintaining physical stability and facilitating communication between the brain and peripheral parts of the body.
413
Spinal Cord: Information Processing
1.2K
The spinal cord is an integral hub for motor and sensory information that enables the brain to communicate with the peripheral nervous system (PNS). This communication consists of relaying sensory data and transmission of motor commands.
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
1.2K

