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Artificial intelligence contouring in radiotherapy for organs-at-risk and lymph node areas
Céline Meyer1, Sandrine Huger2, Marie Bruand1
1Academic Department of Radiation Therapy & Brachytherapy, Institut de Cancérologie de Lorraine - Alexis-Vautrin CLCC - Unicancer, 6 avenue de Bourgogne - CS 30 519, 54 511, Vandoeuvre-Lès-Nancy Cedex, France.
Radiation Oncology (London, England)
|November 22, 2024
Summary
This study evaluated eight artificial intelligence (AI) software programs for radiotherapy contouring. MVision and Limbus showed promise for adult CT scans, while MVision excelled for pediatric CT scans, and TheraPanacea for adult brain MRIs.
Area of Science:
- Radiotherapy and Medical Imaging
- Artificial Intelligence in Healthcare
- Radiation Oncology
Background:
- Organ-at-risk (OAR) and lymph node delineation in radiotherapy is critical but time-consuming and variable.
- Artificial intelligence (AI) offers a potential solution for standardizing and expediting this contouring process.
- This study aimed to assess the technical aspects and accuracy of available AI software for OAR and lymph node contouring.
Purpose of the Study:
- To compare the performance of eight AI software programs for contouring organs-at-risk and lymph node areas.
- To evaluate AI software accuracy against current international contouring recommendations.
- To analyze technical characteristics and clinical usability of AI contouring tools.
Main Methods:
- A blinded study involving 20 radiation oncologists scoring contours generated by eight AI programs.
- Evaluation included adult CT scans, pediatric CT scans, and adult brain MRI scans.
- A scoring scale of 1-3 was used, with an average score >= 2 defining high-performing AI software.
Main Results:
- For adult CT scans, MVision (2.13) and Limbus (2.03) achieved overall average scores > 2.
- For pediatric CT scans, MVision was the only program with an overall average score > 2 (2.07).
- For adult brain MRIs, TheraPanacea demonstrated the highest scores for brain delineation (2.75) and OARs (2.09).
Conclusions:
- MVision and Limbus are recommended for delineating OARs and lymph nodes on adult CT scans in clinical practice.
- MVision is the only efficient AI program for pediatric CT scans.
- TheraPanacea is the most effective AI program for adult brain MRI contouring.

