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Updated: Jun 6, 2025
Mammosphere Formation Assay from Human Breast Cancer Tissues and Cell Lines
Published on: March 22, 2015
[Inflammatory Breast Cancers: Epidemiological Aspects At The Gabriel Touré University Hospital In Bamako, Mali]
D Kasse1,2, M Traoré1,2, F M Sidibé3
1Département de gynécologie au Centre Hospitalier Universitaire Gabriel TOURE, Bamako, Mali.
Introduction:
Inflammatory breast cancer (IBC) is very rare worldwide. The objectives of the present study were to determine the frequency, to describe the socio-demographic and clinical characteristics according to the type of CIS (primary and secondary), and to establish the prognosis.
Method:
We conducted a retrospective cohort study in the Gynecology-Obstetrics unit of CHU Gabriel Touré (2015 - 2021). Data were analyzed using descriptive statistics and the Kaplan Meier method was used to produce survival curves.
Results:
We identified 100 cases of IBC among 588 breast cancer cases including 23 cases of primary IBC (3.59%) and 77 cases of secondary IBC (13.1%). The two types of IBC appeared in a relatively younger and peaked between 35 and 40 years old. Contrary to primary IBC, secondary IBC exhibited a second peak between 55 and 60 years old (Wilcoxon rank, test p > 0.05). The time between symptom onset to disease progression was significantly shorter in primary IBC cases versus secondary one (p < 0.001). Overall survival and specific survival according to the type of IBC were less than 40% after 60 months of followed up.
Conclusion:
The incidence of IBC was high in our setting but dominated by secondary IBC. Whatever the type of IBC, the prognosis was poor.
