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Age changes in Corpus Callosum among Indian cadaver specimens: a normative study.
P Singh1, R Gupta1, A K Nayyar1
1Department of Anatomy, All India Institute of Medical Sciences, Jodhpur, India.
La Clinica Terapeutica
|November 25, 2024
Summary
This study establishes normative morphometric data for the corpus callosum across different age groups. This anatomical information is crucial for neurosurgeons performing transcallosal procedures and for clinicians interpreting brain scans.
Area of Science:
- Neuroanatomy
- Neurosurgery
- Radiology
Background:
- Corpus callosotomy requires detailed knowledge of corpus callosum anatomy and morphometry.
- Normative data on corpus callosum morphometry across age groups is essential for surgical planning.
Purpose of the Study:
- To establish normative data for the morphometry of the corpus callosum in human cadavers.
- To provide anatomical references for neurosurgical procedures and radiological interpretations.
Main Methods:
- Utilized 30 fresh human cadaveric brain specimens.
- Measured the length and thickness of various parts of the corpus callosum (genu, body, splenium, rostrum).
- Data collected across distinct age groups: 25-45, 45.1-65, 65.1-85, and >85 years.
Main Results:
- Mean length of the corpus callosum ranged from 76.91 mm (25-45 years) to 69.28 mm (>85 years).
- Thickness of the genu, body, splenium, and rostrum varied across age groups, with specific mean values provided for each segment and age bracket.
- Significant variations in morphometric parameters were observed with advancing age.
Conclusions:
- The established normative data aids neurosurgeons in performing transcallosal surgeries more safely.
- This data is valuable for psychiatrists and radiologists in analyzing patient scans, particularly those with psychiatric conditions.
