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Related Concept Videos

The Nativist Approach01:21

The Nativist Approach

34
The nativist approach to infant cognitive development proposes that infants are born with inherent knowledge structures that allow them to interpret the world almost immediately. This perspective contrasts with earlier developmental theories, such as those proposed by Jean Piaget, which emphasized a more gradual acquisition of cognitive abilities through interaction with the environment. One key concept in this approach is object permanence — the understanding that objects continue to...
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Development of Immunocompetence01:22

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288
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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Parent Perspectives on Nirsevimab for Their Newborn.

Sarah Hinderstein1, Elena Aragona2, Jaspreet Loyal2

  • 1Yale School of Public Health, New Haven, Connecticut.

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|November 26, 2024
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Summary
This summary is machine-generated.

Parents have knowledge gaps and concerns regarding nirsevimab for respiratory syncytial virus (RSV) prevention in infants. Addressing misinformation and building trust with healthcare providers are key to increasing nirsevimab uptake.

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Area of Science:

  • Pediatric Infectious Diseases
  • Public Health

Background:

  • Nirsevimab, a monoclonal antibody for respiratory syncytial virus (RSV) prevention, was approved for infants in 2023.
  • Bronchiolitis, a common pediatric hospitalization cause, can be prevented by RSV prophylaxis.

Purpose of the Study:

  • To explore parental responses to nirsevimab recommendations for newborns.
  • To understand factors influencing nirsevimab decision-making in parents of healthy infants.

Main Methods:

  • Semistructured interviews with parents of newborns (November 2023 - February 2024).
  • Thematic analysis using the Health Beliefs Model to identify decision-making factors.

Main Results:

  • Parental nirsevimab uptake intentions were divided: 38% planned to use it, 25% did not, and 38% were unsure.
  • Key themes included knowledge gaps about RSV prophylaxis, trust in pediatricians, fear of RSV, concerns about side effects, and misinformation linking nirsevimab to COVID-19 vaccines.
  • The Health Beliefs Model identified opportunities to improve decision-making regarding perceived susceptibility, disease severity, benefits, barriers, and cues to action.

Conclusions:

  • Enhancing awareness of nirsevimab and RSV is crucial for infant protection.
  • Initiating discussions during pregnancy can combat misinformation and foster informed decisions.
  • Leveraging trust in pediatricians and prenatal clinicians can improve nirsevimab uptake.