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Patient Misconceptions About Hyaluronic Acid Fillers: Experience-based Considerations.

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Safety and Effectiveness of Poly-L-Lactic Acid (PLLA-SCA) for Improvement in the Appearance of Cellulite.

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Injectable Poly-L-Lactic Acid for Body Aesthetic Treatments: An International Consensus on Evidence Assessment and

Alessandra Haddad1,2, Luiz Avelar3, Sabrina G Fabi4

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Poly-L-lactic acid collagen stimulator (PLLA-SCA) offers promising results for non-facial body rejuvenation, addressing concerns like sagging and cellulite. Expert consensus provides evidence-based guidelines for effective injection protocols and evaluation tools for aesthetic body treatments.

Keywords:
BiostimulatorBody aestheticsBody rejuvenationPLLA-SCAPoly-l-lactic acid

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Area of Science:

  • Aesthetics and Dermatology
  • Biostimulators
  • Non-invasive Body Contouring

Background:

  • Increasing patient demand for non-facial (body) rejuvenation to complement facial aesthetics.
  • Poly-L-lactic acid collagen stimulator (PLLA-SCA), approved for facial use, is being evaluated for body indications like cellulite.
  • Existing evidence is primarily from observational studies and case series.

Purpose of the Study:

  • To provide an expert-led, evidence-based consensus on PLLA-SCA for body aesthetic and rejuvenation procedures.
  • To establish recommendations for injection protocols across various body sites.
  • To identify appropriate evaluation tools for assessing aesthetic improvements.

Main Methods:

  • Convened international experts in aesthetics, plastic surgery, and dermatology with PLLA-SCA experience.
  • Leveraged 14 years of off-face treatment experience.
  • Developed consensus recommendations based on existing evidence and expert clinical practice.

Main Results:

  • PLLA-SCA shows potential benefits for aesthetic treatments of the neck, knees, abdomen, hands, and upper arms.
  • Improvements in sagging, wrinkling, dimpling, and cellulite can be achieved with sustained results and minimal side effects.
  • Need for standardized injection protocols and validated clinical evaluation tools for body applications.

Conclusions:

  • PLLA-SCA is a viable option for various body rejuvenation procedures, offering sustained aesthetic improvements.
  • Standardization of injection techniques and evaluation metrics is crucial for consistent outcomes.
  • Further systematic evaluations are underway to strengthen the evidence base for body applications.