1927 nm Diode Laser for Infraorbital Hyperpigmentation in Skin of Color: Safe and Effective Approach

Area of Science:

• Dermatology
• Aesthetic Medicine
• Laser Therapy

Background:

• Infraorbital hyperpigmentation (IOH) is a common concern, particularly in individuals with skin of color (SOC).
• Managing IOH is challenging due to the periorbital area's delicate nature and risks associated with energy-based treatments.
• Post-inflammatory hyperpigmentation is a significant concern with many existing IOH treatments.

Purpose of the Study:

• To assess the clinical effectiveness and safety of a 1927 nm non-ablative fractional diode laser for treating IOH.
• To evaluate this laser's suitability for patients with skin of color (SOC).

Main Methods:

• A case series involving 4 female patients with Fitzpatrick skin types III-IV and IOH.
• Treatment utilized the 1927 nm Clear + Brilliant Permea® laser with eight non-ablative fractional passes.
• Outcomes were assessed via physician observation and patient satisfaction, with minimal adjunctive topical therapies.

Main Results:

• All patients showed progressive improvement in periorbital pigmentation, skin brightness, and texture.
• Noticeable results appeared within weeks and were sustained over time.
• No adverse events, including post-inflammatory hyperpigmentation, were reported.

Conclusions:

• The 1927 nm diode laser is a safe and effective treatment for IOH in patients with SOC.
• Its favorable safety profile and gradual improvement make it promising for addressing IOH's pigmentary and structural aspects.
• Further controlled studies are recommended to confirm these findings.