Related Experiment Video
Updated: Aug 13, 2026
09:42
A Chronic Autoimmune Dry Eye Rat Model with Increase in Effector Memory T Cells in Eyeball Tissue
Published on: June 7, 2017
[Sjögren syndrome in childhood]
Klinische Monatsblatter Fur Augenheilkunde
|January 1, 1986
Summary
This case study highlights diagnostic challenges in a 7-year-old girl with keratoconjunctivitis sicca, a rare condition in children. It reviews literary data on Sjögren
Area of Science:
- Ophthalmology
- Rheumatology
- Pediatrics
Background:
- Sjögren's syndrome is a chronic autoimmune disease primarily affecting exocrine glands.
- Childhood-onset Sjögren's syndrome is rare and often presents with diagnostic challenges.
- Keratoconjunctivitis sicca, or dry eye, is a common manifestation of Sjögren's syndrome.
Observation:
- A 7-year-old girl presented with symptoms of keratoconjunctivitis sicca.
- The initial presentation posed diagnostic difficulties.
- Systemic symptoms were evaluated to rule out or confirm Sjögren's syndrome.
Findings:
- The case underscores the complexities in diagnosing Sjögren's syndrome in pediatric patients.
- Diagnostic delays can occur due to the rarity and varied presentations in children.
- Review of existing literature provides insights into childhood Sjögren's syndrome.
Implications:
- Early recognition and diagnosis of Sjögren's syndrome in children are crucial for timely management.
- Increased awareness among pediatricians and ophthalmologists is needed for this rare condition.
- Further research into the pediatric manifestations of Sjögren's syndrome is warranted.
Related Concept Videos
01:43Sex-linked Disorders
Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
01:29Autoimmune Disorders
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...
Concept and Mechanism of Autoimmune Diseases
The immune system...
01:30Tonsillitis I: Introduction
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
01:24Nephrotic Syndrome I : Introduction
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
01:26Nephrotic Syndrome II : Assessment and Medical Management
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document any history...
01:13Asthma III: Clinical Manifestations
Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...