Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anorexia Nervosa01:28

Anorexia Nervosa

46
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
46
Ethnic Identity within a Larger Culture01:27

Ethnic Identity within a Larger Culture

30
Adolescents from ethnic minority backgrounds face a multifaceted journey in forming their identities, shaped by the intersections of cultural expectations and personal exploration. For these adolescents, identity formation involves not only typical developmental challenges but also navigating the perceptions and attitudes of the majority culture. As they grow, adolescents in ethnic minority groups often become increasingly aware of stereotypes, social biases, and discrimination, all of which...
30
Borderline Personality Disorder01:25

Borderline Personality Disorder

36
Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
36
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

44
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
44
Stress and Mental Health01:30

Stress and Mental Health

77
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
77
Stereotypes, Prejudice, and Discrimination02:55

Stereotypes, Prejudice, and Discrimination

90.0K
Humans are very diverse and although we share many similarities, we also have many differences. The social groups we belong to help form our identities (Tajfel, 1974). These differences may be difficult for some people to reconcile, which may lead to prejudice toward people who are different. Prejudice is a negative attitude and feeling toward an individual based solely on one’s membership in a particular social group (Allport, 1954; Brown, 2010). Prejudice is common against people who...
90.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Health and psychosocial differences between binary transgender and nonbinary adults: A national probability sample analysis.

Psychiatry research·2026
Same author

Exploring social and environmental mechanisms as predictors of mental health among young adults with perinatal HIV infection and exposure.

AIDS care·2026
Same author

Place Security and Mental Health: Two Sides of the Same Coin Among Young Adults with Perinatally-Acquired HIV and Exposure in New York City.

AIDS and behavior·2025
Same author

Gender identity invalidation and suicide risk among trans and nonbinary individuals.

Journal of affective disorders·2025
Same author

Forms of transphobia and their influence on health outcomes among transgender, nonbinary, and gender diverse individuals: a global systematic review.

International journal of transgender health·2025
Same author

Masculinizing Testosterone Therapy Reduces the Incidence of PIK3CA-Mutant/ER⁺ Breast Cancer but Not BRCA1-Associated Triple-Negative Breast Cancer.

medRxiv : the preprint server for health sciences·2025
Same journal

Heterogeneity in sexual identity development among young sexual minority cisgender women: Associations with outness, victimization, and depression.

Psychology of sexual orientation and gender diversity·2026
Same journal

Changes in sexual identity and family support: A cohort analysis.

Psychology of sexual orientation and gender diversity·2026
Same journal

Health Disparities Between Stress-Related Mental Health Conditions and Chronic Physical Health Conditions Among Hispanic and Latinx Sexual and Gender Minority Individuals: Findings from the All of Us Research Program.

Psychology of sexual orientation and gender diversity·2026
Same journal

A Daily Diary Study of Discrimination and Substance Use in Transgender and Nonbinary Adults.

Psychology of sexual orientation and gender diversity·2026
Same journal

Discrimination, relationship quality, and the mental health of sexual minority men in relationships: A test of the psychological mediation hypothesis.

Psychology of sexual orientation and gender diversity·2026
Same journal

Structural Minority Stress Predicts Suicidality, Substance Use, and Sexual Risk Behaviors among Sexual Minority Adolescents.

Psychology of sexual orientation and gender diversity·2026
See all related articles

Related Experiment Video

Updated: Jun 6, 2025

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

1.4K

Invalidation and Mental Health among Nonbinary Individuals.

Kelly C Johnson1, Allen J LeBlanc2, Curtis Dolezal3

  • 1Yale University.

Psychology of Sexual Orientation and Gender Diversity
|November 27, 2024
PubMed
Summary
This summary is machine-generated.

Gender identity invalidation, the refusal to accept someone's gender identity, negatively impacts transgender and nonbinary individuals' mental health. This minority stressor is particularly prevalent among nonbinary people, affecting their well-being.

Keywords:
invalidationmental healthminority stressnonbinarytransgender

More Related Videos

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

3.2K
Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
06:58

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

7.3K

Related Experiment Videos

Last Updated: Jun 6, 2025

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice
07:15

Author Spotlight: Understanding Adolescent Social Adversity Effects on Neurodevelopment in Mice

Published on: March 15, 2024

1.4K
Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

3.2K
Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
06:58

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

7.3K

Area of Science:

  • Psychology
  • Sociology
  • Gender Studies

Background:

  • Minority stress significantly impacts transgender and nonbinary (TNB) individuals' mental health.
  • Gender identity invalidation, defined as the refusal to accept a person's gender identity, is a unique stressor within this population.
  • Existing research has not extensively examined the role of invalidation as a minority stressor.

Purpose of the Study:

  • To examine the prevalence and impact of gender identity invalidation among a diverse sample of TNB adults.
  • To investigate the relationship between invalidation, nonbinary gender identity, and mental health outcomes.
  • To identify invalidation as a potential mediator of mental health disparities in gender diverse populations.

Main Methods:

  • Quantitative survey of 302 transgender and nonbinary adults.
  • Utilized a novel 17-item scale to assess experiences of gender identity invalidation across social contexts.
  • Employed multivariate regression models controlling for sociodemographic factors and other minority stress indicators.

Main Results:

  • TNB adults reported low average levels of invalidation, but a minority experienced high levels.
  • Nonbinary participants reported significantly higher invalidation experiences than binary transgender peers.
  • Nonbinary gender identity was independently associated with poorer mental health, mediated by invalidation.

Conclusions:

  • Gender identity invalidation is a significant minority stressor for TNB individuals, particularly nonbinary individuals.
  • Invalidation warrants further research as a key factor influencing mental health in gender diverse populations.
  • Addressing invalidation may be crucial for improving mental health support for transgender and nonbinary communities.