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Published on: May 14, 2012
User-Friendliness Evaluation of Handling pMDI with Various Add-on Devices in Asthmatic Patients
Ahmed M Abdelfattah1, Rania M Sarhan2, Yasmin M Madney2
1Clinical Pharmacy Department, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Ras Sudr, 46612, Egypt.
Abstract:
The objective of this study was to assess the use of pMDI alone and pMDI with different spacers in asthmatic patients and to identify any associations between errors in handling the device for the first time and the sessions needed to reach the correct handling method, considering patient demographics and clinical characteristics. A total of 150 Asthmatic patients were crossed over to handle pMDI alone and with add-on inhalable devices (Aerochamber plus, Tips Haler, Able, Dispozable and Aer-8) randomly, without receiving verbal or demonstrative instruction (baseline assessment). The assessment of the inhaler technique was performed using checklists that had been set beforehand. Subsequently, the proper utilization of the inhaler was exhibited, and the patient's inhaler usage was reassessed. The demonstration was repeated until an optimal technique was attained. The number of counselling attempts required to achieve successful management, together with patient demographics and clinical factors, were documented. The mean percentage of total errors at baseline shows that pMDI alone is significantly higher than pMDI attached to add-on devices (53.90 ± 9.71, 32.54 ± 13.93, 24.53 ± 14.93, 21.6 ± 14.48, 25.14 ± 10.99, 27.47 ± 10.28) for pMDI alone, Aerochamber plus, Tips Haler, Able, Dispozable and Aer-8 respectively at p < 0.01. Able and Tips Haler spacers are significantly lower than other spacers with pMDI and pMDI alone in terms of total sessions needed to attain the complete optimal handling technique at p < 0.01. Weak and very weak correlations were observed between the percentage of total errors at baseline and the total sessions with education years, Montreal Cognitive Assessment, and age as well as some demographics and clinical variables. Handling pMDI can be challenging however the introduction of spacers simplifies this procedure. Different spacers cannot be treated as a homogeneous group due to variations in handling techniques and ease of use. the Able spacer requires the fewest handling steps of any spacer and has the highest percentage of patients who can use it without assistance.
Insights
Metered-dose inhalers (pMDIs) alone are difficult for asthma patients to use correctly. Spacers significantly improve pMDI handling, with the Able and Tips Haler devices requiring fewer sessions for optimal technique.
Area of Science:
- Respiratory Medicine
- Pharmaceutical Technology
Background:
- Metered-dose inhalers (pMDIs) are common asthma medications.
- Correct inhaler technique is crucial for effective drug delivery.
- pMDI use can be challenging for patients, leading to suboptimal treatment.
Purpose of the Study:
- To evaluate the efficacy of pMDIs alone versus with various spacers in asthmatic patients.
- To identify factors influencing the learning curve for correct inhaler technique.
- To compare the ease of use and handling errors associated with different pMDI spacers.
Main Methods:
- 150 asthmatic patients were assessed for pMDI technique without instruction.
- Patients were then trained on using pMDIs with and without five different spacers (Aerochamber plus, Tips Haler, Able, Dispozable, Aer-8).
- Technique was reassessed after demonstration until optimal handling was achieved; number of sessions and errors were recorded.
Main Results:
- pMDI alone had significantly more handling errors (53.9%) at baseline compared to pMDIs with spacers.
- Able and Tips Haler spacers required significantly fewer training sessions for optimal technique.
- Weak correlations were found between baseline errors and patient demographics/cognitive scores.
Conclusions:
- Spacers simplify pMDI use for asthma patients.
- Different spacers vary in handling difficulty and effectiveness.
- The Able spacer demonstrated the fewest handling steps and highest patient success rate without assistance.
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