[3 cases of obstructive ventilation disorder caused by chronic butanedione exposure]

This paper analyzed and discussed 3 cases of the occupational diseases diagnosis and identification of obstructive ventilation disorder caused by chronic butanedione exposure. 3 patients developed recurrent cough 3 months to 2 years after occupational exposure to butanedione. After the activity, the chest tightness and shortness of breath were the main symptoms. Pulmonary function tests presented with ventilatory dysfunction. And the patients were diagnosed as obstructive pulmonary disease caused by occupational chronic butanedione poisoning. It is suggested that butanedione could cause lung ventilation function injury, and provided a basis for the formulation of butanedione occupational exposure limit value and occupational disease diagnosis standard in China.