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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Jun 11, 2026

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

Published on: April 24, 2020

Posterior chamber pseudophakes in glaucoma patients.

L B McMahan, M L Monica, T J Zimmerman

Ophthalmic Surgery

|March 1, 1986

Summary

Cataract surgery with intraocular lens (IOL) implantation improved or maintained intraocular pressure (IOP) control in most glaucoma patients. Postoperative medication needs were significantly reduced, indicating a positive impact on glaucoma management.

Area of Science:

Ophthalmology
Glaucoma Research
Cataract Surgery

Background:

Glaucoma has historically been a contraindication for intraocular lens (IOL) implantation during cataract surgery.
This study investigates the safety and efficacy of posterior chamber IOL implantation in patients with glaucoma.

Observation:

The study included 46 eyes of patients with glaucoma undergoing cataract extraction and IOL implantation.
Intraocular pressure (IOP) control was assessed for three months postoperatively.

Findings:

56.5% of eyes showed improved IOP control, and 41.3% maintained similar IOP control post-surgery.
A total of 97.8% of eyes experienced either improved or unchanged IOP control.
Preoperative glaucoma medication was required for 100% of eyes, while only 41% needed medication postoperatively.

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Last Updated: Jun 11, 2026

Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments

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Implications:

Posterior chamber IOL implantation appears safe and beneficial for IOP management in glaucoma patients undergoing cataract surgery.
This approach may reduce the need for glaucoma medications, simplifying patient care.
Ophthalmologists can consider IOL implantation in glaucoma patients with improved confidence in IOP control.