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Published on: December 1, 2023
Exercise-Induced Laryngeal Obstruction History, Mechanisms, and Diagnostics Across the Globe
Gustavo I Centeno-Saenz1, Rita R Patel2, Timothy Mickleborough3
1Department of Research in Tobacco and COPD, National Institute of Respiratory Diseases, 4502 Calzada de Tlalpan, Tlalpan, Mexico City 14080, Mexico.
Abstract:
Exercise-induced laryngeal obstruction (EILO) poses several diagnostic and management challenges. This review explores EILO's historical evolution, complex nomenclature, global epidemiology, clinical presentation, diagnostic modalities, and underlying pathophysiological mechanisms. Recent efforts to standardize terminology, includes EILO as a subcategory of the broader disorder of inducible laryngeal obstruction. EILO prevalence ranges from 5% to 8%, primarily affecting adolescents and young adults. EILO diagnosis remains challenging, with continuous laryngoscopy during exercise emerging as the gold standard. Multidisciplinary collaboration and adoption of standardized assessments are vital for effective management. Future research should focus on elucidating underlying mechanisms, optimizing diagnostic strategies, and improving EILO-specific outcomes.
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