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CP ANGLE MEDULLOBLASTOMA WITH SUPRATENTORIAL DROP METS.
Muhammad Assad Javed1, Ain Us Saba2, Niaz Ahmed3
1Akbar Niazi Teaching Hospital, IMDC, Islamabad.
Journal of Ayub Medical College, Abbottabad : JAMC
|November 29, 2024
Summary
This case report highlights a rare instance of medulloblastoma in the cerebellopontine angle of a young adult. The tumor later metastasized to the supratentorial region two years post-treatment.
Area of Science:
- Neuro-oncology
- Central Nervous System Tumors
- Pediatric and Adult Oncology
Background:
- Medulloblastoma is a rare embryonic neuroepithelial tumor, predominantly affecting children.
- Adult-onset medulloblastoma, especially in unusual locations like the cerebellopontine angle (CPA), is exceedingly uncommon.
- Cerebellopontine angle (CPA) medulloblastomas rarely exhibit supratentorial extension.
Observation:
- A 17-year-old male presented with occipital headache and gait disturbance.
- MRI revealed a right cerebellopontine angle lesion with cerebellar mass effect.
- Histopathology confirmed medulloblastoma; the patient underwent surgery, chemoradiotherapy, and surveillance.
Findings:
- Two years post-treatment, the patient developed headaches and seizures.
- Follow-up MRI showed a supratentorial lesion in the right temporal lobe with extra-axial components.
- Histopathology of the recurrent tumor again confirmed medulloblastoma.
Implications:
- This case underscores the possibility of late supratentorial metastasis in adult medulloblastoma, even from an initial CPA location.
- It emphasizes the importance of long-term surveillance for medulloblastoma patients, regardless of initial tumor site or age.
- Highlights the need for further research into the metastatic potential and behavior of medulloblastoma in adult populations.
