Related Experiment Video
Updated: Jun 6, 2025

Homogeneous Time-resolved Förster Resonance Energy Transfer-based Assay for Detection of Insulin Secretion
Published on: May 10, 2018
[Pharmacological Treatment for Type 2 Diabetes]
Hideaki Otsuka1, Tomoko Nagamine, Masato Iwabu
1Department of Endocrinology, Metabolism and Nephrology, Graduate School of Medicine, Nippon Medical School.
Abstract:
Diabetes management primarily aims to achieve a life expectancy and quality of life similar to that of people without diabetes. The key to achieving this goal is the effective prevention and management of both the microvascular and macrovascular complications associated with diabetes. Although glycated hemoglobin levels of less than 7% are recommended to minimize complications, individual targets should be set considering variables such as age, duration of diabetes, risk of hypoglycemia, organ function, support system, general health status, and social background. Treatment decisions should be individualized according to each patient's diabetes status and guided by the latest evidence on diabetes pharmacotherapy.
Related Concept Videos
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Diabetes Mellitus: Type 2 and Gestational
Oral Hypoglycemic Agents: Biguanides and Glitazones
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Glucagon-like Receptor Agonists
GLP-1, when administered in high doses intravenously, triggers insulin secretion, inhibits glucagon release, slows gastric emptying, reduces food intake, and restores normal insulin secretion. However, its rapid inactivation by...

