Airborne micro- and nanoplastics: emerging causes of respiratory diseases

Airborne micro- and nanoplastics (AMNPs) are ubiquitously present in human living environments and pose significant threats to respiratory health. Currently, much research has been conducted on the relationship between micro- and nanoplastics (MNPs) and cardiovascular and gastrointestinal diseases, yet there is a clear lack of understanding regarding the link between AMNPs and respiratory diseases. Therefore, it is imperative to explore the relationship between the two. Recent extensive studies by numerous scholars on the characteristics of AMNPs and their relationship with respiratory diseases have robustly demonstrated that AMNPs from various sources significantly influence the onset and progression of respiratory conditions. Thus, investigating the intrinsic mechanisms involved and finding necessary preventive and therapeutic measures are crucial. In this review, we primarily describe the fundamental characteristics of AMNPs, their impact on the respiratory system, and the intrinsic toxic mechanisms that facilitate disease development. It is hoped that this article will provide new insights for further research and contribute to the advancement of human health.