Related Experiment Video
Updated: Jun 5, 2025
08:18
Design and Use of a Full Flow Sampling System FFS for the Quantification of Methane Emissions
Published on: June 12, 2016
16.7K
The persistent problem of persistent air-leaks: approach to management
George Mundanchira1, Laura Frye2, Janani Reisenauer3
1Division of Pulmonary, Critical Care and Sleep Medicine, Northwell, New Hyde Park, New York.
Current Opinion in Pulmonary Medicine
|December 5, 2024
Summary
Persistent air leaks present a challenge for surgeons. Noninvasive therapies like sealants and valves offer alternatives when surgery isn't an option, but more research is needed.
Area of Science:
- Thoracic surgery
- Pulmonology
- Interventional pulmonology
Background:
- Persistent air leaks (PALs) lasting over 5 days are a significant clinical challenge.
- Current guidelines recommend surgical intervention, but many patients are not surgical candidates.
- Conservative management leads to prolonged hospital stays and increased morbidity.
Purpose of the Study:
- To review noninvasive therapies for managing persistent air leaks.
- To evaluate alternatives for patients unsuitable for immediate surgical intervention.
Main Methods:
- Review of noninvasive therapies including sealants, Heimlich valves, chemical and autologous blood patch pleurodesis, and endobronchial valves.
- Evaluation of treatment efficacy and patient suitability.
Main Results:
- Noninvasive options such as autologous blood patch, pleurodesis, and endobronchial valves may provide viable alternatives for managing air leaks in non-surgical candidates.
- Various sealants and valves have been explored as potential treatments.
Conclusions:
- Noninvasive therapies show promise for managing persistent air leaks.
- Further comparative research is necessary before these treatments can be incorporated into clinical guidelines.
Related Concept Videos
01:20Cavity Drainage and Flashings in Masonry walls
72
Typically, a cavity wall consists of two wythes separated by a gap of at least 2 inches, which may contain insulation while still maintaining a minimum clear space of 1 inch to facilitate adequate drainage. Advanced methods like the insertion of a continuous drainage mat can further reduce this space while ensuring effective moisture expulsion.
Weep holes, strategically placed at the base of the cavity, are critical for draining accumulated water. These openings are created by leaving head...
Weep holes, strategically placed at the base of the cavity, are critical for draining accumulated water. These openings are created by leaving head...
72
01:23Measurement of Air Content in Concrete
120
Air content measurement in concrete is critical for ensuring structural integrity and durability of concrete structures, especially in environments prone to severe weather conditions. Accurate air content analysis optimizes concrete's resistance to freeze-thaw cycles and enhances its workability and strength. Several methods are standardized under ASTM guidelines to measure the air content in fresh concrete, each suitable for different concrete types and conditions.
The pressure method,...
The pressure method,...
120
01:25Design Example: Designing a Residential Plumbing System
378
The design of residential plumbing systems requires carefully evaluating water demand, flow rates, and pressure dynamics to ensure both efficiency and reliability. The nature of water flow within pipes is defined by its Reynolds number, which classifies flow as either laminar (smooth) or turbulent.
378
01:29Acute Respiratory Failure-V
123
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
Ensure that patients are monitored continuously for their response to therapy, including changes in...
123
01:27Air-entraining Agents
76
Air-entraining agents improve the durability and workability of concrete in climates with frequent freezing and thawing. These agents prevent cracks by introducing small air bubbles into the mix, creating spaces accommodating water expansion when temperatures drop. The air-entraining agents lower the surface tension of water, forming stable, small air bubbles. This method is more effective than having accidental large voids, as the intentional, smaller, and evenly distributed air voids improve...
76
01:13Mortar Joint Deterioration in Masonry
104
Mortar joint deterioration is a significant concern in masonry structures, with water accumulation in the joints leading to damage from freeze-thaw cycles. The repeated expansion of water during freezing and its melting during thawing develop and propagate cracks in the masonry joints. Eventually, this leads to the spalling of mortar from the joints, loosening masonry units and weakening the structure. The deteriorated mortar joints are also vulnerable to moisture intrusion into the walls.
The...
The...
104