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Updated: May 5, 2026

Ole Isacson: Development of New Therapies for Parkinson's Disease
Published on: April 29, 2007
[Taro Okamoto and Parkinson's Disease]
1Department of General Internal Medicine, National Center of Neurology and Psychiatry (NCNP) National Center Hospital.
Abstract:
Taro Okamoto, a famous Japanese artist, theorist, and writer developed Parkinson's disease during the later years of life. Facial pareidolia associated with Parkinson's disease led to the idea of "Glass with Face." Color vision impairment and reduced contrast sensitivity affected the use of colors in his paintings, and the focus of his creative activities shifted from painting to ceramics and sculpture. In this study, we investigated the effects of anti-Parkinson drugs on Okamoto's creativity. Additionally, we have discussed the etiology of acute respiratory failure that led to Okamoto's death.
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