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Updated: Jun 5, 2025

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients
Published on: March 29, 2022
Differences in anterior ocular biometric characteristics among 6-year-old children with different myopic shift rates:
Yu Zhao1, Yuhao Ye1, Jingbin Geng1
1Eye Institute and Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China; Key Laboratory of Myopia and Related Eye Dieases, Chinese Academy of Medical Sciences, Shanghai, China; NHC Key Laboratory of Myopia and Related Eye Diseases (Fudan University), Shanghai, China; Shanghai Research Center of Ophthalmology and Optometry, China; Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (20DZ2255000), China; Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai, China.
Background:
To investigate longitudinal changes in anterior ocular features during slow and fast myopic shift in 6-year-old children.
Methods:
In total, 242 eyes of first-year primary school children in Shanghai, China, were included in this study. All children underwent an initial examination and were subsequently followed-up for two years. All participants underwent comprehensive examinations, including ocular biometric assessment and cycloplegic autorefraction. Children were divided into two groups based on the degree of myopic shift in 2 years: group A (slow myopic shift, < 1.0 D, N = 145) and group B (fast myopic shift, > 1.0 D, N = 88). Detailed anterior ocular biometric data were compared between the two groups.
Results:
In both groups, the axial length and anterior chamber depth (ACD) increased significantly over the follow-up period (P < 0.001). Anterior corneal surface curvature showed a flattening trend in both flat and steep meridians in group A, while these parameters exhibited steepening changes in group B. Lens thickness (LT) decreased significantly from 3.60 ± 0.20 mm to 3.45 ± 0.17 mm in group B (P < 0.001), but not in group A (P = 0.387). The average lens tilt significantly decreased from 5.21 ± 1.26° to 4.95 ± 1.23° in group A (P = 0.043), but it exhibited no significant change in group B (P = 0.181). Furthermore, LT and ACD were significantly correlated with spherical equivalent changes (P < 0.01).
Conclusions:
Children with slow and fast myopic shift demonstrated comparable ACD deepening changes but showed distinct variations in corneal curvature and lens characteristics.
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