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Updated: Jun 6, 2026
07:13
An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
Published on: December 7, 2016
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Multimodal Pilot Evaluation of a Hyaluronic Acid Infraorbital Filler Using Precise, Multipositional, 3-Dimensional
Aesthetic Surgery Journal. Open Forum
|December 13, 2024
Summary
Hyaluronic acid (HA) filler, Volbella XC, effectively reduces undereye hollows for 90 days, improving patient appearance. Different HA fillers show varied behavior and placement in the infraorbital area.
Area of Science:
- Aesthetic medicine
- Dermatology
- Plastic surgery
Background:
- High demand for infraorbital fillers exists.
- Debate continues regarding injection techniques, anatomical placement, and hyaluronic acid (HA) filler behavior in the infraorbital area.
Purpose of the Study:
- To enhance clinical and anatomical understanding of infraorbital HA injections.
- To evaluate the efficacy and behavior of Volbella XC in the tear trough region.
Main Methods:
- Prospective study involving patient injections of Volbella XC into the tear trough.
- 3D photogrammetry for volumetric measurements and FACE-Q for patient-reported outcomes over 90 days.
- Cadaveric analysis of Juvéderm Vycross and Restylane NASHA in the infraorbital and malar regions.
Main Results:
- Volbella XC demonstrated 70-81% volume maintenance at 30 days and 50-70% at 90 days.
- Significant improvements in eye appearance, overall facial aesthetics, and cheekbones reported (P < .05).
- Cadaver study revealed differences in anatomical location and behavior post-manipulation between Juvéderm and Restylane.
Conclusions:
- Volbella XC effectively augments undereye volume and improves patient-reported outcomes.
- Increased knowledge of HA filler behavior in the infraorbital area can lead to better patient results.
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