Reversible Lubricating Layer for Improving the Endoscope Field with High Transparency and Antipollution Property.

Area of Science:

• Biomaterials Science
• Medical Device Technology
• Surface Chemistry

Background:

• Endoscopes require clear visibility, often hindered by biological fluid adhesion.
• Existing self-cleaning coatings lack transparency and sustainability for lens applications.

Purpose of the Study:

• To develop a transparent, sustainable, and effective self-cleaning coating for endoscopes.
• To create a biomimetic reversible lubricating layer (RL-layer) inspired by ocular structures.

Main Methods:

• Fabrication of a biomimetic RL-layer with low-adhesion and high-transparency properties.
• Demonstration of easy removal of biological fluids, including coagulated blood, due to low surface tension.
• Utilizing fluoride ions to achieve reversible modification of the coating for sustainable use.

Main Results:

• The RL-layer maintained clear endoscopic vision in vivo, even in mucus-filled environments.
• The coating exhibited excellent biocompatibility during in vivo experiments.
• Demonstrated effective removal of biological contaminants and reversible modification capabilities.

Conclusions:

• The biomimetic RL-layer offers a promising solution for maintaining endoscope visibility.
• The reversible and transparent nature of the coating highlights its potential for sustainable medical applications.
• This approach provides a valuable reference for developing self-cleaning coatings in diverse fields.