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Updated: Jun 4, 2025
Compact Quantum Dots for Single-molecule Imaging
Published on: October 9, 2012
Synthesis of N-Doped Graphene Quantum Dots from Cellulose and Construction of a Fluorescent Probe for 6-Mercaptopurin
Qiang Xu1,2, Jiayi Dong3, Guiqin Yan3
1College of Environmental Science and Engineering, Shanxi University of Electronic Science and Technology, Linfen 041004, China.
Abstract:
With cellulose as the precursor and ethylenediamine as the N source, N-doped graphene quantum dots (N-GQDs) were synthesized by a simple and feasible one-pot hydrothermal method. The whole process did noSchemet need a strong acid or strong base and avoided interference from inorganic salt residues. The whole process lasted only 3 h and avoided any complex postprocessing. Because of the outstanding optical properties of N-GQDs, a high-efficiency 6-mercaptopurine fluorescent probe based on the inner filter effect of fluorescence was established. The detection range was 0.2-60 μM and the detection limit was 0.05 μM. This method can preliminarily detect 6-mercaptopurine in human urine and avoids any sample preparation or extraction in advance and brings satisfactory results.
