Related Experiment Video
Updated: Jun 4, 2025

06:16
Subconjunctival Administration of Adeno-associated Virus Vectors in Small Animal Models
Published on: March 16, 2022
2.8K
Subconjunctival dirofilariasis in a healthy subject: a case report
Amirhossein Aghajani1, Mohammad Taher Rajabi1, Seyed Mohsen Rafizadeh1
1Department of Oculo-Facial Plastic and Reconstructive Surgery, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Journal of Ophthalmic Inflammation and Infection
|December 18, 2024
Summary
Subconjunctival dirofilariasis, a rare parasitic eye infection caused by Dirofilaria immitis, can present as an inflammatory mass. Surgical removal and histopathology are key for diagnosis and successful treatment.
Area of Science:
- Ophthalmology
- Parasitology
- Veterinary Medicine
Background:
- Ocular dirofilariasis is a rare parasitic infection.
- Dirofilaria immitis, commonly known as heartworm, can infect humans, particularly in ocular and adnexal tissues.
- Subconjunctival presentation is uncommon and can mimic other inflammatory lesions.
Purpose of the Study:
- To present a case of subconjunctival dirofilariasis.
- To highlight the clinical presentation and diagnostic challenges.
- To emphasize the importance of prompt surgical and histopathological evaluation.
Main Methods:
- A case report of a 20-year-old male with a subconjunctival mass.
- Surgical excision of the lesion.
- Histopathological examination to identify the nematode.
- Postoperative treatment with oral ivermectin.
Main Results:
- Histopathology confirmed an immature Dirofilaria immitis nematode.
- The patient experienced significant lesion resolution after treatment.
- No recurrence was observed during a 6-month follow-up period.
Conclusions:
- Ocular dirofilariasis requires prompt surgical excision and histopathological confirmation.
- Complete excision and appropriate antiparasitic treatment lead to favorable outcomes.
- Early diagnosis and management are crucial for preventing complications.

