Related Experiment Video
Updated: Jun 4, 2025

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Initial Experience With Safety and Efficacy of Endoscopic Full-Thickness Resection in Patients With Inflammatory
Himsikhar Khataniar1, Aakash Desai2, Gursimran S Kochhar2
1Department of Internal Medicine, Allegheny General Hospital, Pittsburgh, PA.
Abstract:
Endoscopic full-thickness resection (EFTR) is a novel endoscopic technique for removing complex colorectal lesions. The inflammatory bowel disease (IBD) population poses unique challenges for endoscopic resection due to an increased prevalence of fibrotic, nonlifting lesions and higher recurrence rates compared with the general population. This case series reports on the successful use of EFTR in 5 patients with IBD who had challenging colonic polyps, including fibrotic and nonlifting lesions. Technical success was achieved in all cases without any postoperative complications. Follow-up surveillance revealed no residual lesions or recurrence, and histopathological analysis confirmed full-thickness resection in all samples. This is one of the first case series suggesting that EFTR is a promising, safe, and effective alternative to surgery for managing complex colorectal polyps in patients with IBD.
More Related Videos
09:42Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
08:26Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Related Concept Videos
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Endoscopic Procedures II: Colonoscopy