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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
meso-5,15-Bis[3-(iso-propyl-idenegalacto-pyran-oxy)phen-yl]-10,20-bis-(4-methyl-phen-yl)porphyrin
Mickey Vinodh1, Fatemeh H Alipour1, Talal F Al-Azemi1
1Department of Chemistry, Kuwait University, PO Box 5969, Safat 13060, Kuwait.
Abstract:
The crystal structure of a glycosyl-ated porphyrin (P_Gal2) system, C70H70N4O12, where two iso-propyl-idene protected galactose moieties are attached to the meso position of a substituted tetra-aryl porphyrin is reported. This structure reveals that the parent porphyrin is planar, with the galactose moieties positioned above and below the porphyrin macrocycle. This orientation likely prevents porphyrin-porphyrin H-type aggregation, potentially enhancing its efficiency as a photosensitizer in photodynamic therapy. Notable non-bonding C-H⋯O and C-H⋯π inter-actions among adjacent P_Gal2 systems are observed in this crystal network. Additionally, the tolyl groups of each porphyrin can engage in π-π inter-actions with the delocalized π-systems of neighboring porphyrins.
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